Device for Endoscopic Treatment of Upper GI Bleed

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When upper gastrointestinal (GI) bleeding occurs, an endoscope is passed through the patient’s esophagus and into the GI tract for a visual assessment of the bleeding location. A major problem in endoscopic management of upper GI bleeding is difficulty identifying the bleeding source because it is often obscured by overlying blood and clots. Traditional efforts of removing blood clots are via lavage (i.e. using large bore gastric tubes or suction through large channel therapeutic endoscopes). These methods often fail to dislodge blood clots that are adherent to the base of the bleeding site. Another method is to remove clots mechanically with a snare. Physicians are generally reluctant to use this latter technique because of the risk of induced bleeding. A clot dissociating composition comprising of hydrogen peroxide and a surfactant can also be used; however, this process is time-consuming and the delay in treatment can lead to serious consequences. These problems have fueled the search for quicker and cost effective ways to attain dissociation of blood clots.

The Endocutter is an endoscope accessory that is designed to be compatible with any single or dual channel endoscope. The device is used in conjunction with the endoscope’s existing suction power, chopping up blood clots and other stomach content before they enter the narrow instrument channel. It consists of a motor with a spinning blade shaft encased in a clear polycarbonate shell that can be attached at the distal end of the endoscope and powered via wiring through the instrument channel. The blade is recessed and surrounded by the shell in order to protect the stomach lining from contact with the blade. The motor is sufficiently small to be placed on the end of the endoscope, while preserving vision through the objective lens and use of the instrument channel. The Endocutter allows the physician to quickly locate the bleeding site without the need for repeated endoscope reinsertions or extended patient stay.

The prototype comprises of several components integrated in the complete design. These components are the protective casing, rubber attachment, motor, blade connector, and blade. The wiring for the prototype can be passed through the instrument channel of the endoscope from the distal end with the help of a guide wire. The end terminals of the wires will be connected to a switch that is integrated with batteries. Rapid prototyping is employed to manufacture the casing, rubber attachment, blade and connector.

Acute GI bleeding accounts for 350,000 to 500,000 hospital admissions in the US each year. The average length of stay varies, but is generally between four and seven days. The average hospital cost for GI bleeding exceeds $5000; most of this cost is incurred from overnight hospital or ICU stays. Thus, a reduction in the length of stay has great potential to reduce costs related to GI bleeding.
Clinical trials are being conducted on pigs at the UofM hospitals under the supervision of GI specialist. The testing conducted so far ratifies the concept and proves the efficiency of the device.

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  • ABOUT THE ENTRANT

  • Name:
    Raghunath Sai Katragadda
  • Type of entry:
    team
    Team members:
    Raghunath Sai Katragadda
    Taarif Jafferi
    Zachary Weingarden
    Rahul Rattan
  • Profession:
    Engineer/Designer
  • Number of times previously entering contest:
    never
  • Raghunath Sai's favorite design and analysis tools:
    Catia, Solidworks, Ansys, Abaqus, Hypermesh, Optistruct, ANSA, GMSH, Meshlab, ISight
  • For managing CAD data Raghunath Sai's company uses:
    SolidWorks PDMWorks
  • Raghunath Sai's hobbies and activities:
    Formula 1 enthusiast, Gadget tech, Gaming
  • Raghunath Sai belongs to these online communities:
    linkedin, medical device group, cae, asme, sae
  • Raghunath Sai is inspired by:
    The need to identify and capture the needs of consumers motivates my designs. A simple design is a most complicated design to achieve. It should cut across professional boundaries for ease of use and understanding.
  • Hardware used for this entry:
    Rapid Prototype Machine, 3D printer, CNC Lathe and Milling machine
    Software used for this entry:
    CATIA, ANSYS, Solidworks
  • Patent status:
    pending