Traditional TURP surgery (Transurethral Resection of the Prostate) for BPH (Benign Prostatic Hyperplasia) removes excess prostate tissue using a heated wire loop with side effects such as death (1%), incontinence (3%), impotence (5%) and retrograde ejaculation (75%). Alternative techniques using lasers use $1,000 disposable fibers but offer greatly reduced incidence of side effects.
Most laser surgery for BPH uses a side firing optical fiber because the tissue masses (prostate gland lobes) surround the urethra through which the fiber gains access. Compared to standard axial delivery fibers, side-fire fibers produce highly divergent and distorted output profiles with up to 35% of the laser energy scattering at surgically useless angles. While laser surgery does offer greater precision in tissue removal than TURP, and far less collateral tissue damage, imprecise energy application does give rise to some complications.
The reduced surgical efficacy necessitates the use of excessive laser power and forces the surgeon to position the fiber very close to the target tissue, risking direct fiber to tissue contact. Tissues adhere within the low energy density fringes of the distorted output, heating the fused quartz to temperatures favoring devitrification and dissolution and pitting the output surface. Surgeons must also overcome the torsion of these almost millimeter diameter quartz fibers to aim the output, further reducing surgical precision.
Modern side-fire fibers use tips polished at the critical angle (for total reflection) of the highest angular modes within the fiber. This highest mode angle limits off-axis redirection to roughly 75° so the best case spot is an ellipse rather than a circle. Worse yet, the reflected energy must exit the cylindrical wall of the fiber and traverse an air gap before passing through the cylindrical wall of the surrounding quartz cap serving to preserve the necessary refractive index difference for the critical angle. These curvatures and refractive index transitions give rise to the bulk of the distortion and scatter. Past attempts at fusing the cap to the fiber output have largely failed; the fibers fracture in use due to residual stresses in the glasses that cannot be dampened by annealing (due to nearby and thermally labile fiber components).
The subject of this entry, ProFlex™ LDD, is lower cost and highly efficient with low divergence and essentially no distortion or scatter. The lateral redirection function is produced within the fiber cap, rather than directly upon the fiber; the optical output path is uniform and the cap is annealed. In removing the lateral redirection function from the fiber, additional optics may be employed to extend the off axis energy redirection to approximately 90° and shape the fiber output.
Due to the low divergence, the new side-fire fiber may standoff from tissue, reducing inadvertent contact and the sharp edges of the output spot offer considerably less territory for tissue adhesion. With the direction of output determined by the orientation of the cap there is no fiber torsion to overcome in targeting tissues. Excess laser power need not be applied and collateral tissue damage may be avoided.
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ABOUT THE ENTRANT
Name: Stephen Griffin
Type of entry: individual
Number of times previously entering contest:3
Stephen's favorite design and analysis
SolidWorks, pencil and paper, whiteboard
Stephen's hobbies and activities:
solar power, electric vehicles, analytical chem
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Linkedin, ACS Network, Facebook, ResearchGate
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Problems are bread and butter to inventors: without them we have little or nothing to do. Finding problems is facilitated by discussions with prominent surgeons, often with a bit of social lubricant, and by viewing surgeries live. Problems that the doctors themselves may not recognize or believed insurmountable are exposed for study..
Software used for this entry:
Patent status: pending