We have developed a Hemoglobin-Electrophoresis Biochip (HemeChip) that can rapidly, easily and conclusively identify the hemoglobin type in blood to diagnose Sickle Cell Disease (SCD) in newborns.
About 3 million people worldwide suffer from SCD, mostly in Africa, India and the Middle East, with an estimated 100,000 affected in the US, according to the Centers for Disease Control and Prevention. SCD affects 1 in 375 newborns in the US. More than 800 children are born with SCD every day in Africa, and more than half of them die in childhood due to lack of diagnosis and early treatment. In the US, hemoglobin screening of newborns is mandated for early diagnosis, so that, monitoring and treatment can be ...
Left hemiplegia is paralysis of the left side of the body due to brain stroke. In brain stroke, brain cells die due to oxygen starvation. If this happens in the right side of the brain then the left side becomes dysfunctional. But since the left side brain is unaffected, the right side of body remains fully functional. Generally, neuro muscular stimulation using surface electrodes placed at the nerve points simulates as if current is coming from the brain and corresponding functional movement will occur. Now physical exercise/physiotherapy is very important for motor recovery. But since the brain is not sending (or incapable of)any signal to initiate the movement, either one has to use active side force movement in inactive side. ...
Even though there are many wheelchair designs existing today still the following needs are not met.
1. There is no specific design for a one armed person
2. Wheelchair that can folded and put into car, bus
3. Ultra light - like in the range of 10-12 kg
4. Intelligent which follow guide the occupant's instructions
5. Which can have maximum tipping angle to avoid tips and falls
6. Which can operate both in powered and manual mode
The solution: i-3waha
i-3triwaha is a first of its kind 3 wheeled wheelchair for a one armed person which can be folded and put into a car. the control is based on an intelligent system, which has 20 ...
Healthcare acquired infections (HAI) are on the rise in our healthcare facilities. Each year, 250,000 blood stream infections occur according to the CDC. This creates a significant expense in terms of both morbidity and financial costs. The IV MAID is a new and innovative device which solves several challenges in healthcare facilities for both clinicians and patients. It is a novel product which provides solutions and benefits.
The IV MAID provides patient centered care. It attaches to the patient's IV Pole, traveling with the patient at all times. It has a locking compartment to house prescription medications needed to care for vascular access devices, providing FDA compliant medication storage at the bedside. This saves clinicians time, up to 6 ...
Using current imaging technology, get measurements of the cartilage space in the joint. Then with a 3 D printer, print the replacement cartilage our of ultrahigh molecular polyethylene (or similar wear resistant polymer). After printing the replacement cartilage, insert it in the joint and fuse to the bone with laser.
This should be able to be done with a small incision and not injuring the ligaments/tendons around the joint.
As 3D printers evolve to allowing printing of various alloys of metals, metal replacement cartilage could become the standard for wear resistance and durability.
This would save major surgery for replacement implants as used ...
A prosthetic device that provides low impact to knee and ankle joints during walking, running.
Uses the enginered rubber joints to take the load of the impact and provide resistance against compacting.
This idea is a concept that can be optimized and manufactured using carbon composites and hi tech materials that are strong and lightweight to fit and support the legs while allowing the energy absorbing rubber joints to minimise the load on the knee and ankle ...
KneeStim intelligently uses neuromuscular electrical stimulation to contract quadriceps muscles in synchrony with patient movement, turning each joint loading instance into a muscle building repetition. This device is intended to provide improved, accelerated, cost-effective rehabilitation assistance to patients managing knee osteoarthritis or recovering from knee replacement surgery.
Quadriceps strength, or lack thereof, correlates with a patient's ability to manage their knee OA or to recovery fully from knee replacement surgery. Physical therapy is necessary to re-strengthen the quadriceps, but cost pressures and reimbursement policies are increasingly limiting the number of PT sessions a patient can have. KneeStim addresses the unmet need for optimized outpatient rehabilitation that focuses on quadriceps re-strengthening while minimizing time and money spent by both patient ...
This invention has to do with biophotonic materials that induce the mitochondrial electron transport chain to improve upon itself and actually prolong life. It is a system that once used can effectively reverse the aging process through the use of light and water. Albeit that it would have to be an invasive property that is able to reach the mitochondrial core so the method would have to be one of an ingested nature.
Surface photon rejuvenation is easily available these days but further research needs to be applied to the sciences of core mitochondrial rejuvenation through the processes of light dissipation to the mitochondrial cell thus increasing the ATP cycle for increased energy to that cell.
Methods for directing ...
Low-voltage dielectrophoresis capillary-driven whole blood chip for point-of-care biomedical diagnostic application
Many microfluidic devices for plasma separation from human blood samples have attracted numerous researchers to develop for point-of-care medical health diagnosis in the future. However, most microfluidic methods required external mechanical driving sources such as a syringe pump and the tube connections between devices and their driving sources. They are not convenient for point-of-care applications and extra energy needs dissipating for driving components. Some dielectrophoresis force can be used for manipulation of microscale and nanoscale particles together with blood samples. But the DEP technique required diluted blood samples and the contact of the samples with the electrodes. The applied voltages were high mostly over 100 V which could damage the red blood cells (RBCs) and the hemoglobin released from ...
The following description is for the MDDS (Micro Drug Delivery System) and does not require an IV connection to the patient. This MDDS pill is swallowed whole and excreted in the excrement. The MDDS "pill" is a HCl acid resistant polymer covered caplet shaped device which contains a remotely programmable and monitored nanocomputer ( RCMnC ) which controls the delivery of up to 4 different drugs of which are active at low doses from .001 mg/1.0 ug up to 25 mg per dose. The RCMnC controls micro pump jets based on ink jet printer head technology however scaled down to allow for onboard attachment within the MDDS pill body.
The 4 micro pump jets are attached ...
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